Is niacinamide acid safe for pregnancy?


Pregnancy is a beautiful and transformative journey in a woman’s life, but it also demands increased attention to health and safety. During this time, expectant mothers are often cautious about what they consume, including skincare products. Niacinamide, also known as vitamin B3, has gained popularity in the skincare industry for its numerous benefits. However, the question remains: Is niacinamide safe for pregnancy? In this article, we will explore the current scientific evidence and expert opinions to shed light on this important topic.

Understanding Niacinamide

Niacinamide, or nicotinamide, is a water-soluble vitamin B3 compound. It plays a vital role in various physiological processes within the body, including converting food into energy, maintaining healthy skin, and supporting nervous system function. As a skincare ingredient, niacinamide has gained recognition for its multiple dermatological benefits, such as improving skin texture, reducing redness, and regulating sebum production.

Absorption and Safety in Pregnancy

One of the primary concerns during pregnancy is whether topical skincare ingredients can be absorbed into the bloodstream and potentially harm the fetus. Fortunately, in the case of niacinamide, there is limited evidence to suggest significant systemic absorption. When applied topically, niacinamide usually stays on the outer layer of the skin and does not penetrate deeply enough to reach the bloodstream. As a result, it is less likely to pose a risk to the developing fetus.

Safety Studies and Expert Opinions

The safety of niacinamide during pregnancy has not been extensively studied in humans, mainly due to ethical considerations. Pregnant women are generally excluded from clinical trials, making it challenging to obtain concrete evidence regarding the safety of specific substances during this period.

However, the available data and expert opinions do not raise significant concerns about the use of niacinamide in topical skincare products during pregnancy. Organizations such as the American Academy of Dermatology and the Organization of Teratology Information Specialists (OTIS) consider niacinamide to be safe for use during pregnancy and breastfeeding when applied to the skin.

Benefits of Niacinamide During Pregnancy

Apart from being deemed safe, niacinamide might even offer some benefits during pregnancy. The hormonal changes that occur during this time can lead to various skin issues, such as increased pigmentation (melasma), acne, and dryness. Niacinamide’s anti-inflammatory properties could help alleviate these concerns and provide relief to expectant mothers seeking ways to manage their changing skin.

Addressing Melasma: Melasma, often referred to as the “mask of pregnancy,” is a common skin condition characterized by dark, pigmented patches on the face. Niacinamide has been shown to inhibit the transfer of melanin (skin pigment) to the upper layers of the skin, making it a potential ally in managing melasma.

Acne Management: Pregnancy-related hormonal fluctuations can trigger acne breakouts in some women. Niacinamide’s ability to regulate sebum production and reduce inflammation could aid in controlling acne symptoms.

Moisture Retention: As pregnancy progresses, some women may experience skin dryness. Niacinamide’s hydrating properties can help retain moisture in the skin, improving overall skin health and comfort.

Alternative Ingredients

While niacinamide appears to be safe for most pregnant women when used topically, some individuals may prefer to err on the side of caution and opt for alternative skincare ingredients during pregnancy. Fortunately, there are several pregnancy-safe alternatives that can deliver similar benefits:

  1. Vitamin C: A potent antioxidant, vitamin C can brighten the skin and help with collagen production.
  2. Hyaluronic Acid: Known for its exceptional moisturizing properties, hyaluronic acid helps keep the skin hydrated.
  3. Azelaic Acid: Effective in addressing acne and melasma, azelaic acid is considered safe during pregnancy.


In conclusion, the use of niacinamide in topical skincare products during pregnancy is generally considered safe. Limited systemic absorption, expert opinions, and the lack of concrete evidence indicating harm support this assertion. Moreover, niacinamide could even offer benefits by addressing common skin concerns that arise during pregnancy.

If you are going to use a Niacinamide serum during pregnancy, it will be best to use a plant-based organic natural niacinamide serum like the I’m Fabulous Cosmetics niacinamide serum.

Know that, as with any skincare product, it is essential for pregnant women to consult with their healthcare provider or dermatologist before incorporating new products into their routine. Individual variations and sensitivities may exist, and professional guidance will ensure the safety and well-being of both the expectant mother and her developing baby.

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